#Pioneer_in_Biomaterials
In NOVUS, we research and develop varieties of biomaterials for medical and veterinary uses. From the chemical building blocks to the products that can be used in surgeries, NOVUS has put tremendous resources in serious researches and productions. Since founded in 2014, NOVUS has grown into a hub of biomaterials with great interests in pushing forward the advancement of material sciences to change the world.
#Technology
Through our state of the art nanomaterial technology, nano-hydroxapatite crystals are successfully grown on nano-co-polymers. The sub-100nm nano-hydroxyapatite crystals have shown the same electron diffraction pattern as human hydroxyapatite crystals extracted from trabeculae in selected area electron diffraction (SAED) in TEM. Sub-500nm nano-co-polymers allow seamless distribution with the polymer matrix which resemble the FDM filament.
In Novus, all nano-particles and crystals are synthesized in industrial scale under close supervision of our engineers and scientists. The incorporation of nano-particles in the polymer matrix during filament extrusion is engineered to produce excellent dispersion and to perfect the printing experience in any commercial 3D printer. All the manufacturing processes are done in ISO 14644-1 Class 10,000 cleanroom and is under strict quality control governed by ISO 13485.
For example, Bonlecule is a groundbreaking functional biomaterial. It has superior biological and mechanical properties compared to any biomaterial building block on the market. Conventional biomaterials improve on bioactivity through filler materials or coatings. In FDM filament, filler materials will contribute to the brittleness and filament may break at the printer nozzle. Coating is also not possible for making uniform continuum required for 3D printing. The solution to this limitation is to utilize bioactive nano-particles with engineered dispersion process during production.
#R&D_and_Production
To meet the high demands of medical technology on materials and components, we offer medical grade filaments that are manufactured to the highest quality standards. Our medical grade 3D printing filaments are the optimal solution for additive manufacturing of medical components. These filaments have been tested resp. evaluated for biocompatibility according to standard ISO 13485, ISO 10993 or USP class VI and meet the specified requirements for contact of up to 24 hours with skin and tissue and, if applicable, indirect contact with blood.
#Case_Study
#CMF
Craniomaxillofacial (CMF) surgery, a specialized field focusing on skull, face, and jaw conditions, integrated with 3D printing technology, which allows the creation of patient-specific implants, surgical guides, and models with enhanced precision and customization. By utilizing digital imaging and computer-aided design software, surgeons can now design and fabricate implants tailored to an individual's unique anatomy. Medical grade 3D printing filaments, eg. Bonlecule, PEEK and PMMA are needed for cranial plates or mandibular reconstructions.
#OMF
Oral and Maxillofacial (OMF) surgery, a specialized branch of surgery focusing on diseases, injuries, and deformities of the face, jaw, and mouth integrated with 3D printing technology. This technology has particularly benefited complex cases such as orthognathic surgery, facial reconstruction, and dental implantology. 3D printing facilitates the use of medical grade 3D printing filaments, like Bonlecule, PMMA and PEEK, which offer strength, durability, and biocompatibility. The integration of 3D printing in OMF surgery has opened new avenues for personalized treatment options, enhanced surgical precision, and improved patient care.
Nilesh, K., Dadhich, A., Shah, S., & Saluja, H. (2022). Three-dimensional printing in maxillofacial surgery: A quantum LEAP in future. National Journal of Maxillofacial Surgery, 13(4), 203. https://doi.org/10.4103/njms.njms_65_20
#GBR
Guided Bone Regeneration (GBR) is a surgical technique used to regenerate bone in areas with bone defects. The procedure involves preparing the surgical site, placing a barrier membrane to prevent soft tissue ingrowth, and filling the defect with bone graft material. A common material used for the barrier membrane is PLLA, which is a biocompatible and resorbable polymer. The PLLA membrane acts as a physical barrier, preventing the intrusion of soft tissue cells into the bone defect while allowing for the migration of bone cells and blood vessels. As the bone regenerates, the PLLA membrane gradually resorbs, leaving behind the newly formed bone.
Giacomo, F. et al. (2009) Guided Bone Regeneration Technique in the Esthetic Zone: A Novel Approach Using Resorbable PLLA-PGA Plates and Screw Fixation. A Case Report
#TKA/THA
Total knee arthroplasty (TKA) or total hip arthroplasty (THA), is a surgical procedure that involves replacing the damaged joint with an artificial joint implant. During this procedure, a bone centralizer is often used to ensure proper alignment and fit of the implant within the bone. The centralizer acts as a guide and helps maintain the correct positioning of the implant during surgery. The centralizer can be customized using medical grade 3D printing filaments, like PEEK, PMMA and Bonlecule. They offer excellent properties, biocompatibility, and radiolucency, making it an ideal choice for orthopedic applications. By utilizing 3D printing, surgeons can create patient-specific centralizers that perfectly match the unique anatomy of each individual.
Morley, J.R., et al. Cemented Total Hip Replacement G. Bentley (ed.), European Surgical Orthopaedics and Traumatology,F DOI 10.1007/978-3-642-34746-7_226
#Testimonials
A Leading University Hospital
"We have been using your Medical Grade 3D Printing Filaments for our surgical applications, and we couldn't be happier with the results. The prints are incredibly accurate, biocompatible, and exhibit excellent strength and durability. The quality of the filament has exceeded our expectations, and it has become our go-to choice for medical-grade prints."
Evonik, Solvay, Invibio, Victex
Dr. Michael Lopez,
Biomat MA Engineer
"Ossfila has developed an advanced and affordable implant solution for my patients. It is a game-changing product to my country. The precision and reliability of the prints have allowed us to create customized implants and surgical guides with exceptional fit and functionality. The biocompatibility and sterilizability of the filaments have been crucial in ensuring patient safety and positive outcomes. We highly recommend your filaments to any medical professional seeking top-quality 3D printing solutions."
Vasim Mulani,
3D Incredible Engineer
"Your technical support team has been exceptional in providing assistance and guidance throughout our 3D printing journey. They have promptly addressed our queries, offering valuable insights and troubleshooting solutions. Their expertise and dedication have played a significant role in our success, and we appreciate their commitment to customer satisfaction."