Bone | Biomaterials | Diagnosis
Here at NOVUS, we put our innovative,
patented technologies into practice,
bringing novel solutions to the market.
Quality-Assured, Compliant Medical Grade Filaments
To meet the demanding requirements of the medical device industry, Novus provides OSSFILA® medical grade 3D printing filaments manufactured to the highest quality standards. Designed specifically for additive manufacturing of medical components and patient-specific implants, OSSFILA filaments offer reliable clinical performance and proven regulatory compliance.
Each OSSFILA® material is evaluated for biocompatibility in accordance with ISO 10993 or USP Class VI standards. All production takes place in an ISO 14644-1 Class 10,000 cleanroom, under strict quality management systems certified to ISO 13485. This comprehensive approach delivers a trusted material solution that gives hospital procurement teams and regulatory bodies the confidence they need to specify Novus materials for clinical use.
Our Flagship Bonlecule™
Through our state of the art nanomaterial technology, nano-hydroxyapatite crystals sized 20 nm are chemically bonded on acrylic based co-polymers which forms the building block of our flagship product, Bonlecule™. Bonlecule™ is a groundbreaking bioactive 3D printing biomaterial that possesses superior biological and mechanical properties. Instead of improving bioactivity through filler materials or coating, which often cause heterogenicity and nozzle blockage during 3D printing, the incorporation of nano-hydroxyapatite coated copolymer is engineered to demonstrate uniform, well-dispersed hydroxyapatite throughout the filament matrix. Transmission electron microscopy confirms the excellent dispersion, enabling smooth, reliable printing on any commercial 3D printers.
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The incorporation of nano-particles in the polymer matrix during filament extrusion is engineered to produce excellent dispersion as proven under transmission electron microscopy and to perfect the printing experience in any commercial 3D printer. All manufacturing takes place in our ISO 14644-1 Class 10,000 cleanroom and is under strict quality control governed by ISO 13485.
What Makes Bonlecule™ Different from Standard Implant Materials?
Most 3D printed implants are made from biologically inert materials: PEEK, PMMA, or titanium. These materials are biocompatible, meaning the body tolerates them. But tolerance is not the same as integration. With inert implants, bone grows up to the implant surface but does not bond with it. Over time, this can lead to micromovement, implant loosening, and in some cases revision surgery.
Bonlecule™ is fundamentally different. It is a bioactive 3D printing filament, the world's first and only of its kind, that actively promotes osseointegration. Bone-forming cells (osteoblasts) recognise the bioactive signals on Bonlecule™'s surface and migrate into the implant over time. The implant does not just fill the space. It becomes part of the patient's bone.
Groundbreaking Nano-Particles
Over the past seven years, we have developed breakthrough nano-material synthesis and nano-coating methods that are now applied in our bone filler formulation and implants. Our nano-coating shares the same basic structure with the body’s natural bone mineral, yielding a higher biocompatibility. The nano-particles that we create can assist bone growth and plays a crucial role in our bone cement and implant formulation.
Clinically Proven
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Our hydroxyapatite-PMMA based Veterinary Adhesives have been clinically proven to mimic the chemical composition of natural bone, enhancing healing and providing immediate stability. They promote greater bone formation compared to conventional PMMA adhesives and exhibit comparable mechanical properties to natural bone, making them suitable for a wide range of species and biomedical applications.